3 papers
q-bio.QM2023
mRNA active transport in oocyte-early embryo: 3D agent-based modeling
Marat A. Sabirov, Ekaterina M. Myasnikova, Alexander V. Spirov
Axes of polarity (and primary morphogenetic gradients) are established in the oocyte - early embryo through active transport and localization of maternal factors. It is the oocyte…
q-bio.QM2019
Heuristic algorithms in Evolutionary Computations and modular organization of biological macromolecules: applications to directed evolution
Alexander Spirov, Ekaterina Myasnikova
A while ago, the ideas of evolutionary biology inspired computer scientists to develop a thriving nowadays field of evolutionary computation (EC), in general, and genetic algorithm…
q-bio.MN2018
Modeling of gap gene regulatory networks in Drosophila with the account of the gene modular structure (in Russian)
Ekaterina Myasnikova, Alexander Spirov
Genes are frequently regulated in complex manners, necessitating modelling approaches which go beyond simple (linear) gene-to-gene interactions and address the modularity of cis-re…