2 papers
stat.ME2021
Parameter estimation in nonlinear mixed effect models based on ordinary differential equations: an optimal control approach
Quentin Clairon, Chloé Pasin, Irene Balelli +2
We present a parameter estimation method for nonlinear mixed effect models based on ordinary differential equations (NLME-ODEs). The method presented here aims at regularizing the…
math.OC2018
Controlling IL-7 injections in HIV-infected patients
Chloé Pasin, François Dufour, Laura Villain +2
Immune interventions consisting in repeated injection are broadly used as they are thought to improve the quantity and the quality of the immune response. However, they also raised…