97 citations · 263 across the 18 of their papers we have counts for
3 papers · 1 filter
Calibrating Generative Models to Distributional Constraints
Henry D. Smith, Nathaniel L. Diamant, Brian L. Trippe
Generative models frequently suffer miscalibration, wherein statistics of the sampling distribution, such as the fraction of generations in a given class, deviate from desired valu…
Predicting mutational effects on protein binding from folding energy
Arthur Deng, Karsten Householder, Fang Wu +3
Accurate estimation of mutational effects on protein-protein binding energies is an open problem with applications in structural biology and therapeutic design. Several deep learni…
MotifBench: A standardized protein design benchmark for motif-scaffolding problems
Zhuoqi Zheng, Bo Zhang, Kieran Didi +5
The motif-scaffolding problem is a central task in computational protein design: Given the coordinates of atoms in a geometry chosen to confer a desired biochemical function (a mot…