17 citations · 51 across the 13 of their papers we have counts for
4 papers · 1 filter
Extending combinatorial regulatory network modeling to include activity control and decay modulation
Bree Cummins, Marcio Gameiro, Tomas Gedeon +3
Understanding how the structure of within-system interactions affects the dynamics of the system is important in many areas of science. We extend a network dynamics modeling platfo…
Genetic Networks Encode Secrets of Their Past
Peter Crawford-Kahrl, Robert R. Nerem, Bree Cummins +1
Research shows that gene duplication followed by either repurposing or removal of duplicated genes is an important contributor to evolution of gene and protein interaction networks…
Operon Dynamics with State Dependent Transcription and/or Translation Delays
Tomas Gedeon, Antony R. Humphries, Michael C. Mackey +3
Transcription and translation retrieve and operationalize gene encoded information in cells. These processes are not instantaneous and incur significant delays. In this paper we st…
Equilibria and their Stability in Networks with Steep Sigmoidal Nonlinearities
William Duncan, Tomas Gedeon, Hiroshi Kokubu +2
In this paper we investigate equilibria of continuous differential equation models of network dynamics. The motivation comes from gene regulatory networks where each directed edge…