34 citations · 169 across the 21 of their papers we have counts for
21 papers
Determining clinically relevant features in cytometry data using persistent homology
Soham Mukherjee, Darren Wethington, Tamal K. Dey +1
Cytometry experiments yield high-dimensional point cloud data that is difficult to interpret manually. Boolean gating techniques coupled with comparisons of relative abundances of…
Connecting the dots across time: Reconstruction of single cell signaling trajectories using time-stamped data
Sayak Mukherjee, David Stewart, William Stewart +2
Single cell responses are shaped by the geometry of signaling kinetic trajectories carved in a multidimensional space spanned by signaling protein abundances. It is however challen…
Limiting energy dissipation induces glassy kinetics in single cell high precision responses
Jayajit Das
Single cells often generate precise responses by involving dissipative out-of-thermodynamic equilibrium processes in signaling networks. The available free energy to fuel these pro…
Maximum Entropy estimation of probability distribution of variables in higher dimensions from lower dimensional data
Jayajit Das, Sayak Mukherjee, Susan E. Hodge
A common statistical situation concerns inferring an unknown distribution Q(x) from a known distribution P(y), where X (dimension n), and Y (dimension m) have a known functional re…
Host-to-host variation of ecological interactions in polymicrobial infections
Sayak Mukherjee, Kristin E. Weimer, Sang-Cheol Seok +5
Host-to-host variability with respect to interactions between microorganisms and multicellular hosts are commonly observed in infection and in homeostasis. However, the majority of…
In silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP4 Mediated Feedbacks Increase Robustness
Sayak Mukherjee, Stephanie Rigaud, Sang-Cheol Seok +7
The inositol-phosphate messenger inositol(1,3,4,5)tetrakisphosphate (IP4) is essential for thymocyte positive selection by regulating plasma-membrane association of the protein tyr…