2 papers
q-bio.QM2019
Parameter Estimation and Uncertainty Quantification for Systems Biology Models
Eshan D. Mitra, William S. Hlavacek
Mathematical models can provide quantitative insight into immunoreceptor signaling, but require parameterization and uncertainty quantification before making reliable predictions.…
q-bio.QM2018
Generalizing Gillespie's direct method to enable network-free simulations
Ryan Suderman, Eshan D. Mitra, Yen Ting Lin +3
Gillespie's direct method for stochastic simulation of chemical kinetics is a staple of computational systems biology research. However, the algorithm requires explicit enumeration…