2 papers
stat.ME2025
A Comparative Evaluation of Statistical Methods in Hybrid Controlled Trials
Di Ran, Fanni Zhang, Sima Shahsavari +3
Randomized clinical trials (RCTs) are widely considered the gold standard for evaluating the effectiveness of new treatments or interventions in drug development. Still, they may n…
q-bio.QM2025
Evaluation of optimal cut-offs and dichotomous combinations for two biomarkers to improve patient selection
Gina DAngelo, Di Ran, Binbing Yu
Background Identifying the right cut-off for continuous biomarkers in clinical trials is important to identify subgroups of patients who are at greater risk of disease or more like…