3 papers
cs.LG2025
On learning functions over biological sequence space: relating Gaussian process priors, regularization, and gauge fixing
Samantha Petti, Carlos MartÃ-Gómez, Justin B. Kinney +2
Mappings from biological sequences (DNA, RNA, protein) to quantitative measures of sequence functionality play an important role in contemporary biology. We are interested in the r…
physics.bio-ph2024
Density estimation for ordinal biological sequences and its applications
Wei-Chia Chen, Juannan Zhou, David M. McCandlish
Biological sequences do not come at random. Instead, they appear with particular frequencies that reflect properties of the associated system or phenomenon. Knowing how biological…
q-bio.BM2024
Strangers in a foreign land: 'Yeastizing' plant enzymes
Kristen Van Gelder, Steffen N. Lindner, Andrew D. Hanson +1
Expressing plant metabolic pathways in microbial platforms is an efficient, cost-effective solution for producing many desired plant compounds. As eukaryotic organisms, yeasts are…