2 papers
stat.ME2025
Robust estimation of causal dose-response relationship using exposure data with dose as an instrumental variable
Jixian Wang, Zhiwei Zhang, Ram Tiwari
An accurate estimation of the dose-response relationship is important to determine the optimal dose. For this purpose, a dose finding trial in which subjects are randomized to a fe…
stat.ME2025
The benefit of dose-exposure-response modeling in the estimation of dose-response relationship and dose optimization: some theoretical and simulation evidence
Jixian Wang, Zhiwei Zhang, Ram Tiwari
In randomized dose-finding trials, although drug exposure data form a part of key information for dose selection, the evaluation of the dose-response (DR) relationship often mainly…