83 citations · 238 across the 9 of their papers we have counts for
3 papers · 1 filter
Semiconservative Replication in the Quasispecies Model
Emmanuel Tannenbaum, Eric J. Deeds, Eugene I. Shakhnovich
This paper extends Eigen's quasispecies equations to account for the semiconservative nature of DNA replication. We solve the equations in the limit of infinite sequence length for…
Protein Evolution within a Structural Space
Eric J. Deeds, Nikolay V. Dokholyan, Eugene I. Shakhnovich
Understanding of the evolutionary origins of protein structures represents a key component of the understanding of molecular evolution as a whole. Here we seek to elucidate how the…
Equilibrium Distribution of Mutators in the Single Fitness Peak Model
Emmanuel Tannenbaum, Eric Deeds, Eugene I. Shakhnovich
This paper develops an analytically tractable model for determining the equilibrium distribution of mismatch repair deficient strains in unicellular populations. The approach is ba…