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physics.bio-ph1999
Serine Proteases: an Ab Initio Molecular Dynamics Study
L. De Santis, P. Carloni
In serine proteases (SP's), the H-bond between His-57 and Asp-102, and that between Gly-193 and the transition state intermediate play a crucial role for enzymatic function. To she…
cond-mat.stat-mech1999
Protein Design is a Key Factor for Subunit-subunit Association
Cecilia Clementi, Paolo Carloni, Amos Maritan
Fundamental questions about the role of the quaternary structures are addressed using a statistical mechanics off-lattice model of a dimer protein. The model, in spite of its simpl…