2 papers
stat.ME2025
Estimands and Their Implications for Evidence Synthesis for Oncology: A Simulation Study of Treatment Switching in Meta-Analysis
Rebecca K. Metcalfe, Antonio Remiro-Azócar, Quang Vuong +4
The ICH E9(R1) addendum provides guidelines on accounting for intercurrent events in clinical trials using the estimands framework. However, there has been limited attention to the…
stat.ME2025
Target Aggregate Data Adjustment Method for Transportability Analysis Utilizing Summary-Level Data from the Target Population
Yichen Yan, Quang Vuong, Rebecca K Metcalfe +3
Transportability analysis is a causal inference framework used to evaluate the external validity of randomized clinical trials (RCTs) or observational studies. Most existing transp…