3 papers
stat.CO2025
CSTEapp: An interactive R-Shiny application of the covariate-specific treatment effect curve for visualizing individualized treatment rule
Yi Zhou, Yuhao Deng, Yu-Shi Tian +5
In precision medicine, deriving the individualized treatment rule (ITR) is crucial for recommending the optimal treatment based on patients' baseline covariates. The covariate-spec…
stat.ME2025
Inference for Cumulative Incidences and Treatment Effects in Randomized Controlled Trials with Time-to-Event Outcomes under ICH E9 (R1)
Yuhao Deng, Shasha Han, Xiao-Hua Zhou
In randomized controlled trials (RCTs) that focus on time-to-event outcomes, intercurrent events can arise in two ways: as semi-competing events, which modify the hazard of the pri…
stat.ME2024
Separable pathway effects of semi-competing risks using multi-state models
Yuhao Deng, Yi Wang, Xiang Zhan +1
Semi-competing risks refer to the phenomenon where a primary event (such as mortality) can ``censor'' an intermediate event (such as relapse of a disease), but not vice versa. Unde…