4 papers
Scaling Up Formal Representation of Clinical Trial Protocols in Ensemble Logic Using LLMs: A Preliminary Study
Yan Huang, Xubing Hao, Xiaojin Li +4
The reliance on unstructured free text for documenting clinical trial protocols creates a significant barrier to automated reasoning, cohort discovery, and trial simulation. The la…
Empowering Clinical Trial Design through AI: A Randomized Evaluation of PowerGPT
Yiwen Lu, Lu Li, Dazheng Zhang +20
Sample size calculations for power analysis are critical for clinical research and trial design, yet their complexity and reliance on statistical expertise create barriers for many…
Information Extraction from Clinical Notes: Are We Ready to Switch to Large Language Models?
Yan Hu, Xu Zuo, Yujia Zhou +9
Backgrounds: Information extraction (IE) is critical in clinical natural language processing (NLP). While large language models (LLMs) excel on generative tasks, their performance…
CDEMapper: Enhancing NIH Common Data Element Normalization using Large Language Models
Yan Wang, Jimin Huang, Huan He +13
Common Data Elements (CDEs) standardize data collection and sharing across studies, enhancing data interoperability and improving research reproducibility. However, implementing CD…