4 papers
Harmonizing the Generation and Pre-publication Stewardship of FAIR Image Data
Nikki Bialy, Frank Alber, Brenda Andrews +44
Alongside molecular insights into genes and proteins, biological imaging holds great promise for deepening scientific understanding of complex cellular systems and advancing predic…
Signal Recovery Using a Spiked Mixture Model
Paul-Louis Delacour, Sander Wahls, Jeffrey M. Spraggins +2
We introduce the spiked mixture model (SMM) to address the problem of estimating a set of signals from many randomly scaled and noisy observations. Subsequently, we design a novel…
Virtual Staining of Label-Free Tissue in Imaging Mass Spectrometry
Yijie Zhang, Luzhe Huang, Nir Pillar +5
Imaging mass spectrometry (IMS) is a powerful tool for untargeted, highly multiplexed molecular mapping of tissue in biomedical research. IMS offers a means of mapping the spatial…
Super-resolution multi-contrast unbiased eye atlases with deep probabilistic refinement
Ho Hin Lee, Adam M. Saunders, Michael E. Kim +15
Purpose: Eye morphology varies significantly across the population, especially for the orbit and optic nerve. These variations limit the feasibility and robustness of generalizing…