99 citations · 100 across the 2 of their papers we have counts for
3 papers
CXCR6, a Newly Defined Biomarker of Tissue-Specific Stem Cell Asymmetric Self-Renewal, Identifies More Aggressive Human Melanoma Cancer Stem Cells
Rouzbeh Taghizadeh, Minsoo Noh, Yang Hoon Huh +8
Background: A fundamental problem in cancer research is identifying the cell type that is capable of sustaining neoplastic growth and its origin from normal tissue cells. Recent in…
Evolutionary dynamics of adult stem cells: Comparison of random and immortal strand segregation mechanisms
Emmanuel Tannenbaum, James L. Sherley, Eugene I. Shakhnovich
This paper develops a point-mutation model describing the evolutionary dynamics of a population of adult stem cells. Such a model may prove useful for quantitative studies of tissu…
Semiconservative replication in the quasispecies model II: Generalization to arbitrary lesion repair probabilities
Emmanuel Tannenbaum, James L. Sherley, Eugene I. Shakhnovich
This paper extends the semiconservative quasispecies equations to account for arbitrary post-replication lesion repair efficiency. Such an extension could be an important tool for…