6 papers
Mixing Performance of Toroidal Ring Mixers: Effects of Flow Rate Ratios and Geometric Asymmetry
Mohammad Majidi, Taehong Kim, Jiaqi Li +4
Microfluidic mixing is important for nanoparticle fabrication, where rapid contact between the solvent and nonsolvent streams is needed to control the formation process. Various mi…
ALL-FEM: Agentic Large Language models Fine-tuned for Finite Element Methods
Rushikesh Deotale, Adithya Srinivasan, Yuan Tian +3
Finite element (FE) analysis guides the design and verification of nearly all manufactured objects. It is at the core of computational engineering, enabling simulation of complex p…
Bayesian Aneurysm Growth Detection via Surface Displacement Modeling
Jorge A. Roa Castro, Abhishek Singh, Atharva Hans +5
Clinical decisions for unruptured intracranial aneurysms depend on detecting growth on follow-up magnetic resonance angiography (MRA). Growth is typically judged from manual 2D dia…
SMURF: Scalable method for unsupervised reconstruction of flow in 4D flow MRI
Atharva Hans, Abhishek Singh, Pavlos Vlachos +1
We introduce SMURF, a scalable and unsupervised machine learning method for simultaneously segmenting vascular geometries and reconstructing velocity fields from 4D flow MRI data.…
VAST: Vascular Flow Analysis and Segmentation for Intracranial 4D Flow MRI
Abhishek Singh, Vitaliy L. Rayz, Pavlos P. Vlachos
Four-dimensional (4D) Flow MRI can noninvasively measure cerebrovascular hemodynamics but remains underused clinically because current workflows rely on manual vessel segmentation…
Effect of Electric Charge on Biotherapeutic Transport, Binding and Absorption: A Computational Study
Mario de Lucio, Pavlos P. Vlachos, Hector Gomez
This study explores the effects of electric charge on the dynamics of drug transport and absorption in subcutaneous injections of monoclonal antibodies (mAbs). We develop a novel m…