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cond-mat.dis-nn2000
Speeding protein folding beyond the Go model: How a little frustration sometimes helps
Steven S. Plotkin
Perturbing a Go model towards a realistic protein Hamiltonian by adding non-native interactions, we find that the folding rate is in general enhanced as ruggedness is initially inc…
cond-mat.dis-nn2000
Structural and Energetic Heterogeneity in Protein Folding
Steven S. Plotkin, Jose N. Onuchic
A general theoretical framework is developed using free energy functional methods to understand the effects of heterogeneity in the folding of a well-designed protein. Native energ…