486 citations · 1.8k across the 25 of their papers we have counts for
25 papers
Spiral defect chaos with intermittency increases mean termination time
Mahesh Kumar Mulimani, Wouter-Jan Rappel
Cardiac models are examples of excitable systems and can support stable spiral waves. For certain parameter values, however, these spiral waves can become unstable, resulting in sp…
Prediction of excitable wave dynamics using machine learning
Mahesh Kumar Mulimani, Sebastian Echeverria-Alar, Michael Reiss +1
Excitable systems can exhibit a variety of dynamics with different complexity, ranging from a single, stable spiral to spiral defect chaos (SDC), during which spiral waves are cont…
Extinction Dynamics of Cardiac Fibrillation
David Vidmar, Wouter-Jan Rappel
During episodes of atrial fibrillation, the heart's electrical activity becomes disorganized and shows fragmenting spiral waves. To systematically address how this pattern terminat…
Cell Motility Dependence on Adhesive Wetting
Yuansheng Cao, Richa Karmakar, Elisabeth Ghabache +6
Adhesive cell-substrate interactions are crucial for cell motility and are responsible for the necessary traction that propels cells. These interactions can also change the shape o…
Cell-to-cell variation sets a tissue-rheology-dependent bound on collective gradient sensing
Brian A. Camley, Wouter-Jan Rappel
When a single cell senses a chemical gradient and chemotaxes, stochastic receptor-ligand binding can be a fundamental limit to the cell's accuracy. For clusters of cells responding…
Crawling and turning in a minimal reaction-diffusion cell motility model: coupling cell shape and biochemistry
Brian A. Camley, Yanxiang Zhao, Bo Li +2
We study a minimal model of a crawling eukaryotic cell with a chemical polarity controlled by a reaction-diffusion mechanism describing Rho GTPase dynamics. The size, shape, and sp…