most citedDynamic Optimization for Monoclonal Antibody Production

1 citations · 1 across the 2 of their papers we have counts for

collaborators

14 papers

math.OC2024

ESDIRK-based nonlinear model predictive control for stochastic differential-algebraic equations

Anders Hilmar Damm Christensen, Nicola Cantisani, John Bagterp Jørgensen

In this paper, we present a nonlinear model predictive control (NMPC) algorithm for systems modeled by semi-explicit stochastic differential-algebraic equations (DAEs) of index 1.…

math.OC2024

Numerical Discretization Methods for the Discounted Linear Quadratic Control Problem

Zhanhao Zhang, Steen Hørsholt, John Bagterp Jørgensen

This study focuses on the numerical discretization methods for the continuous-time discounted linear-quadratic optimal control problem (LQ-OCP) with time delays. By assuming piecew…

q-bio.QM2024

Identification of PK-PD Insulin Models using Experimental GIR Data

Kirstine Sylvest Freil, Liv Olivia Fritzen, Dimitri Boiroux +2

We present a method to estimate parameters in pharmacokinetic (PK) and pharmacodynamic (PD) models for glucose insulin dynamics in humans. The method combines 1) experimental gluco…

q-bio.QM20241 cited

Modeling principles for a physiology-based whole-body model of human metabolism

Laura Hjort Blicher, Peter Emil Carstensen, Jacob Bendsen +4

Physiological whole-body models are valuable tools for the development of novel drugs where understanding the system aspects is important. This paper presents a generalized model t…

q-bio.QM2024

A whole-body mathematical model of cholesterol metabolism and transport

Peter Emil Carstensen, Jacob Bendsen, Laura Hjort Blicher +2

Cardiovascular diseases are the leading cause of death. Increased levels of plasma cholesterol are consistently associated with an increased risk of cardiovascular disease. As a re…

eess.SY20241 cited

Electrification of Clay Calcination: A First Look into Dynamic Modeling and Energy Management for Integration with Sustainable Power Grids

Bruno Laurini, Nicola Cantisani, Wilson R. Leal da Silva +2

This article explores the electrification in clay calcination, proposing a dynamic model and energy management strategy for the integration of electrified calcination plants into s…