2 papers
stat.AP2025
Evaluating Bias Reduction Methods in Binary Emax Model for Reliable Dose-Response Estimation
Jiangshan Zhang, Vivek Pradhan, Yuxi Zhao
The Binary Emax model is widely employed in dose-response analysis during Phase II clinical studies to identify the optimal dose for subsequence confirmatory trials. The parameter…
stat.ME2024
Robust Emax Model Fitting: Addressing Nonignorable Missing Binary Outcome in Dose-Response Analysis
Jiangshan Zhang, Vivek Pradhan, Yuxi Zhao
The Binary Emax model is widely employed in dose-response analysis during drug development, where missing data often pose significant challenges. Addressing nonignorable missing bi…