2 papers
cs.LG2025
CellCLIP -- Learning Perturbation Effects in Cell Painting via Text-Guided Contrastive Learning
Mingyu Lu, Ethan Weinberger, Chanwoo Kim +1
High-content screening (HCS) assays based on high-throughput microscopy techniques such as Cell Painting have enabled the interrogation of cells' morphological responses to perturb…
q-bio.QM2024
Modeling variable guide efficiency in pooled CRISPR screens with ContrastiveVI+
Ethan Weinberger, Ryan Conrad, Tal Ashuach
Genetic screens mediated via CRISPR-Cas9 combined with high-content readouts have emerged as powerful tools for biological discovery. However, computational analyses of these scree…