5 papers
Suppression of errors in collectively coded information
Martin J. Falk, Leon Zhou, Yoshiya J. Matsubara +3
Modern life largely transmits genetic information from mother to daughter through the duplication of single physically intact molecules that encode information. However, copying an…
Simple biological controllers drive the evolution of soft modes
Christopher Joel Russo, Kabir Husain, Rama Ranganathan +2
Biological systems, with many interacting components, face high-dimensional environmental fluctuations, ranging from diverse nutrient deprivations to toxins, drugs, and physical st…
Ecosystems as adaptive living circuits
Ankit Dhanuka, Avi I. Flamholz, Arvind Murugan +1
Unlike many physical nonequilibrium systems, in biological systems, the coupling to external energy sources is not a fixed parameter but adaptively controlled by the system itself.…
Temporal Contrastive Learning through implicit non-equilibrium memory
Martin J. Falk, Adam T. Strupp, Benjamin Scellier +1
The backpropagation method has enabled transformative uses of neural networks. Alternatively, for energy-based models, local learning methods involving only nearby neurons offer be…
Soft Modes as a Predictive Framework for Low Dimensional Biological Systems across Scales
Christopher Joel Russo, Kabir Husain, Arvind Murugan
All biological systems are subject to perturbations: due to thermal fluctuations, external environments, or mutations. Yet, while biological systems are composed of thousands of in…