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q-bio.MN2004
The architecture of the protein domain universe
Nikolay V. Dokholyan
Understanding the design of the universe of protein structures may provide insights into protein evolution. We study the architecture of the protein domain universe, which has been…
q-bio.BM2004
Can contact potentials reliably predict stability of proteins?
Jainab Kahtun, Sagar D. Khare, Nikolay V. Dokholyan
The simplest approximation of interaction potential between amino-acids in proteins is the contact potential, which defines the effective free energy of a protein conformation by a…