2 papers
q-bio.MN2017
High-throughput validation of ceRNA regulatory networks
Hua-Sheng Chiu, María Rodríguez Martínez, Mukesh Bansal +5
Background: MicroRNAs (miRNAs) play multiple roles in tumor biology [1]. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive s…
q-bio.GN2017
Inferring clonal composition from multiple tumor biopsies
Matteo Manica, Hyunjae Ryan Kim, Roland Mathis +14
Explicit accounting for copy number alterations can dramatically improve mutation frequency estimates, leading to more accurate phylogeny reconstructions and subclone characterizat…