2 papers
cs.LG2025
Lightweight MSA Design Advances Protein Folding From Evolutionary Embeddings
Hanqun Cao, Xinyi Zhou, Zijun Gao +7
Protein structure prediction often hinges on multiple sequence alignments (MSAs), which underperform on low-homology and orphan proteins. We introduce PLAME, a lightweight MSA desi…
cs.LG2025
Protein Inverse Folding From Structure Feedback
Junde Xu, Zijun Gao, Xinyi Zhou +6
The inverse folding problem, aiming to design amino acid sequences that fold into desired three-dimensional structures, is pivotal for various biotechnological applications. Here,…