2 papers
stat.AP2022
A Bayesian framework for genome-wide inference of DNA methylation levels
Marcel Hirt, Axel Finke, Alexandros Beskos +4
DNA methylation is an important epigenetic mark that has been studied extensively for its regulatory role in biological processes and diseases. WGBS allows for genome-wide measurem…
q-bio.QM2017
Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection
James E. Barrett, Andrew Feber, Javier Herrero +4
Motivation: Epigenetic heterogeneity within a tumour can play an important role in tumour evolution and the emergence of resistance to treatment. It is increasingly recognised that…