activity
20042010
most citedQuasispecies Theory for Multiple-Peak Fitness Landscapes

70 citations · 163 across the 5 of their papers we have counts for

collaborators

5 papers

q-bio.PE2010★ 52 cited

Quasispecies theory for finite populations

Jeong-Man Park, Enrique Munoz, Michael W. Deem

We present stochastic, finite-population formulations of the Crow-Kimura and Eigen models of quasispecies theory, for fitness functions that depend in an arbitrary way on the numbe…

q-bio.PE2009★ 12 cited

Solution of the Crow-Kimura and Eigen models for alphabets of arbitrary size by Schwinger spin coherent states

Enrique Munoz, Jeong-Man Park, Michael W. Deem

To represent the evolution of nucleic acid and protein sequence, we express the parallel and Eigen models for molecular evolution in terms of a functional integral representation w…

q-bio.PE2008★ 29 cited

Quasispecies Theory for Horizontal Gene Transfer and Recombination

Enrique Munoz, Jeong-Man Park, Michael W. Deem

We introduce a generalization of the parallel, or Crow-Kimura, and Eigen models of molecular evolution to represent the exchange of genetic information between individuals in a pop…

q-bio.PE2006★ 70 cited

Quasispecies Theory for Multiple-Peak Fitness Landscapes

D. B. Saakian, E. Munoz, Chin-Kun Hu +1

We use a path integral representation to solve the Eigen and Crow-Kimura molecular evolution models for the case of multiple fitness peaks with arbitrary fitness and degradation fu…

q-bio.BM2004

Epitope analysis for influenza vaccine design

Enrique T. Munoz, Michael W. Deem

Until now, design of the annual influenza vaccine has relied on phylogenetic or whole-sequence comparisons of the viral coat proteins hemagglutinin and neuraminidase, with vaccine…