22 citations · 53 across the 6 of their papers we have counts for
6 papers
Coarse-grained modeling of protein unspecifically bound to DNA
Carlo Guardiani, Massimo Cencini, Fabio Cecconi
There is now a certain consensus that Transcription Factors (TFs) reach their target sites, where they regulate gene transcription, via a mechanism dubbed facilitated diffusion (FD…
Computational analysis of folding and mutation properties of C5 domain from Myosin binding protein C
Carlo Guardiani, Fabio Cecconi, Roberto Livi
Thermal folding Molecular Dynamics simulations of the domain C5 from Myosin Binding Protein C were performed using a native-centric model to study the role of three mutations relat…
Testing simplified protein models of the hPin1 WW domain
Fabio Cecconi, Carlo Guardiani, Roberto Livi
The WW domain of the human Pin1 protein for its simple topology and the large amount of experimental data is an ideal candidate to assess theoretical approaches to protein folding.…
A toy model of polymer stretching
Carlo Guardiani, Franco Bagnoli
We present an extremely simplified model of multiple-domains polymer stretching in an atomic force microscopy experiment. We portray each module as a binary set of contacts and dec…
A microscopic model of evolution of recombination
Franco Bagnoli, Carlo Guardiani
We study the evolution of recombination using a microscopic model developed within the frame of the theory of quantitative traits. Two components of fitness are considered: a stati…
A model of sympatric speciation through assortative mating
Franco Bagnoli, Carlo Guardiani
A microscopic model is developed, within the frame of the theory of quantitative traits, to study both numerically and analytically the combined effect of competition and assortati…