112 citations · 271 across the 6 of their papers we have counts for
6 papers
Early life imprints the hierarchy of T cell clone sizes
Mario U. Gaimann, Maximilian Nguyen, Jonathan Desponds +1
The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors. While clonal selection in response to particular antigens has been studied in…
Hunchback promoters can readout morphogenetic positional information in less than a minute
Jonathan Desponds, Massimo Vergassola, Aleksandra M. Walczak
The first cell fate decisions in the developing fly embryo are made very rapidly : hunchback genes decide in a few minutes whether a given nucleus follows the anterior or the poste…
Receptor crosstalk improves concentration sensing of multiple ligands
Martin Carballo-Pacheco, Jonathan Desponds, Tatyana Gavrilchenko +5
Cells need to reliably sense external ligand concentrations to achieve various biological functions such as chemotaxis or signaling. The molecular recognition of ligands by surface…
Population dynamics of immune repertoires
Jonathan Desponds, Andreas Mayer, Thierry Mora +1
The evolution of the adaptive immune system is characterized by changes in the relative abundances of the B- and T-cell clones that make up its repertoires. To fully capture this e…
Precision of readout at the hunchback gene: analyzing short transcription time traces in living fly embryos
Jonathan Desponds, Huy Tran, Teresa Ferraro +7
The simultaneous expression of the hunchback gene in the numerous nuclei of the developing fly embryo gives us a unique opportunity to study how transcription is regulated in livin…
Fluctuating fitness shapes the clone size distribution of immune repertoires
Jonathan Desponds, Thierry Mora, Aleksandra M. Walczak
The adaptive immune system relies on the diversity of receptors expressed on the surface of B and T-cells to protect the organism from a vast amount of pathogenic threats. The prol…