activity
20172026
most citedMechRetro is a chemical-mechanism-driven graph learning framework for interpretable retrosynthesis prediction and pathway planning

124 citations · 132 across the 6 of their papers we have counts for

collaborators

8 papers

q-bio.GN2026

Panoramic modelling of single-cell transcriptomes at scale with CellNet

Xiaoqing Lian, Pei Liu, Jiahui Tan +5

Comprehensively characterizing cellular diversity is critical for understanding tissue development, identifying disease-associated populations and investigating gene programmes lin…

cs.AI2026

Understanding Gene Expression-to-Image Learning: Spatial Structure and Information Fidelity

Xiaoqing Lian, Pei Liu, Jiahui Tan +3

Single-cell RNA sequencing (scRNA-seq) enables cell-level analysis of biological heterogeneity, but learning effective representations from high-dimensional, unordered gene express…

cs.LG2022★ 124 cited

MechRetro is a chemical-mechanism-driven graph learning framework for interpretable retrosynthesis prediction and pathway planning

Yu Wang, Chao Pang, Yuzhe Wang +5

Leveraging artificial intelligence for automatic retrosynthesis speeds up organic pathway planning in digital laboratories. However, existing deep learning approaches are unexplain…

cs.LG2019★ 3 cited

Reference-Based Sequence Classification

Zengyou He, Guangyao Xu, Chaohua Sheng +2

Sequence classification is an important data mining task in many real world applications. Over the past few decades, many sequence classification methods have been proposed from di…

cs.LG2019★ 5 cited

Instance-Based Classification through Hypothesis Testing

Zengyou He, Chaohua Sheng, Yan Liu +1

Classification is a fundamental problem in machine learning and data mining. During the past decades, numerous classification methods have been presented based on different princip…

cs.LG2017

HPSLPred: An Ensemble Multi-label Classifier for Human Protein Subcellular Location Prediction with Imbalanced Source

Shixiang Wan, Quan Zou

Predicting the subcellular localization of proteins is an important and challenging problem. Traditional experimental approaches are often expensive and time-consuming. Consequentl…

cs.DC2017

HAlign-II: efficient ultra-large multiple sequence alignment and phylogenetic tree reconstruction with distributed and parallel computing

Shixiang Wan, Quan Zou

Multiple sequence alignment (MSA) plays a key role in biological sequence analyses, especially in phylogenetic tree construction. Extreme increase in next-generation sequencing res…

q-bio.QM2017

Pretata: predicting TATA binding proteins with novel features and dimensionality reduction strategy

Quan Zou, Shixiang Wan, Ying Ju +2

Background: It is necessary and essential to discovery protein function from the novel primary sequences. Wet lab experimental procedures are not only time-consuming, but also cost…