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q-bio.QM2020
Increased peak detection accuracy in over-dispersed ChIP-seq data with supervised segmentation models
Arnaud Liehrmann, Guillem Rigaill, Toby Dylan Hocking
Motivation: Histone modification constitutes a basic mechanism for the genetic regulation of gene expression. In early 2000s, a powerful technique has emerged that couples chromati…
q-bio.QM2014★ 34 cited
Performance evaluation of DNA copy number segmentation methods
Morgane Pierre-Jean, Guillem Rigaill, Pierre Neuvial
A number of bioinformatic or biostatistical methods are available for analyzing DNA copy number profiles measured from microarray or sequencing technologies. In the absence of rich…