5 papers
Kidney function and kidney failure prediction in a large multiethnic population
James A. Diao, Morgan Sanchez, Adir Sommer +7
Background: Patients with chronic kidney disease (CKD) experience worsening kidney function and develop subsequent kidney failure at different rates. Accurate estimates of a patien…
Laboratory Trajectories Improve Kidney Failure Risk Estimation
Morgan Sanchez, James A. Diao, Jesse Cummings +8
Accurate kidney failure risk assessment is critical to timely intervention in chronic kidney disease (CKD). Existing equations (e.g. Kidney Failure Risk Equation; KFRE) rely on sin…
Learning Normal Representations for Blood Biomarkers
Aashna P. Shah, Michelle M. Li, Yash Lal +9
Blood-based biomarkers underpin clinical diagnosis and management, yet their interpretation relies largely on fixed population reference intervals that ignore stable, intra-patient…
Statin Recommendations among US Adults with the 2026 Dyslipidemia Guidelines
James A. Diao, Thomas A. Buckley, Andrew Z. Zhou +3
Importance: The 2026 multisociety dyslipidemia guideline recommended the PREVENT equations in place of the PCE equations, introduced 30-year risk assessment as a new treatment path…
Disentangling Proxies of Demographic Adjustments in Clinical Equations
Aashna P. Shah, James A. Diao, Emma Pierson +2
The use of coarse demographic adjustments in clinical equations has been increasingly scrutinized. In particular, adjustments for race have sparked significant debate with several…