2 papers
stat.ME2020
Connecting Instrumental Variable methods for causal inference to the Estimand Framework
Jack Bowden, Bjoern Bornkamp, Ekkehard Glimm +1
Causal inference methods are gaining increasing prominence in pharmaceutical drug development in light of the recently published addendum on estimands and sensitivity analysis in c…
stat.AP2017
Response adaptive designs for binary responses: how to offer patient benefit while being robust to time trends?
Sofia S. Villar, Jack Bowden, James Wason
Response-adaptive randomisation (RAR) can considerably improve the chances of a successful treatment outcome for patients in a clinical trial by skewing the allocation probability…