activity
20042024
most citedAlzheimer's disease: analysis of a mathematical model incorporating the role of prions

65 citations · 121 across the 8 of their papers we have counts for

collaborators

8 papers

q-bio.NC2024

Oscillations in neuronal activity: a neuron-centered spatiotemporal model of the Unfolded Protein Response in prion diseases

Elliot M. Miller, Tat Chung D. Chan, Carlos Montes-Matamoros +3

Many neurodegenerative diseases (NDs) are characterized by the slow spatial spread of toxic protein species in the brain. The toxic proteins can induce neuronal stress, triggering…

math.DS2023★ 4 cited

A multigroup approach to delayed prion production

Mostafa Adimy, Abdennasser Chekroun, Laurent Pujo-Menjouet +1

We generalize the model proposed in [Adimy, Babin, Pujo-Menjouet, \emph{SIAM Journal on Applied Dynamical Systems} (2022)] for prion infection to a network of neurons. We do so by…

physics.bio-ph2022

A qualitative analysis of a A-monomer model with inflammation processes for Alzheimer's disease

Ionel Ciuperca, Laurent Pujo-Menjouet, Leon Matar-Tine +2

We introduce and study a new model for the progression of Alzheimer's disease incorporating the interactions of A-monomers, oligomers, microglial cells and interleukins with neu…

q-bio.BM2015★ 13 cited

First passage times in homogeneous nucleation: dependence on the total number of particles

Romain Yvinec, Samuel Bernard, Erwan Hingant +1

Motivated by nucleation and molecular aggregation in physical, chemical and biological settings, we present an extension to a thorough analysis of the stochastic self-assembly of a…

math.CA2013★ 65 cited

Alzheimer's disease: analysis of a mathematical model incorporating the role of prions

Mohamed Helal, Erwan Hingant, Laurent Pujo-Menjouet +1

We introduce a mathematical model of the in vivo progression of Alzheimer's disease with focus on the role of prions in memory impairment. Our model consists of differential equati…

math.AP2011★ 13 cited

Fragmentation and monomer lengthening of rod-like polymers, a relevant model for prion proliferation

Ionel Sorin Ciuperca, Erwan Hingant, Liviu Iulian Palade +1

The Greer, Pujo-Menjouet andWebb model [Greer et al., J. Theoret. Biol., 242 (2006), 598-606] for prion dynamics was found to be in good agreement with experimental observations un…