71 citations · 484 across the 27 of their papers we have counts for
3 papers · 1 filter
Normal and pathological dynamics of platelets in humans
Gabriel P. Langlois, Morgan Craig, Antony R. Humphries +6
We develop a comprehensive mathematical model of platelet, megakaryocyte, and thrombopoietin dynamics in humans. We show that there is a single stationary solution that can undergo…
Oscillations in a maturation model of blood cell production
Ivana Drobnjak, A. C. Fowler, Michael C. Mackey
In this paper we use a continuous model to describe the development of a single cell lineage following the committal of stem cells. Three separate controls are implemented in the m…
Periodic Oscillations of Blood Cell Populations in Chronic Myelogenous Leukemia
Michael C. Mackey, Chunhua Ou, Laurent Pujo-Menjouet +1
We develop some techniques to prove analytically the existence and stability of long period oscillations of stem cell populations in the case of periodic chronic myelogenous leukem…