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stat.ME2025
A Statistical Framework for Co-Mediators of Zero-Inflated Single-Cell RNA-Seq Data
Seungjun Ahn, Li Chen, Maaike van Gerwen +2
Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of cellular heterogeneity, enabling detailed molecular profiling at the individual cell level. However, integrat…
stat.ME2025
A Multi-Omics Framework for Survival Mediation Analysis of High-Dimensional Proteogenomic Data
Seungjun Ahn, Weijia Fu, Maaike van Gerwen +2
Survival analysis plays a crucial role in understanding time-to-event (survival) outcomes such as disease progression. Despite recent advancements in causal mediation frameworks fo…