91 citations · 243 across the 11 of their papers we have counts for
12 papers
Optimal concentration and gradient sensing by perfect monitors
Farshid Jafarpour
Cells often estimate chemical concentrations from only a few diffusing molecules, whose stochastic motion limits sensing precision. We consider a perfect monitoring instrument that…
Optimal information transmission in a sequential model for cell division
Krishna P. Ramachandran, Motasem ElGamel, Farshid Jafarpour +1
In proliferating cell populations, adaptive changes to biochemical reactions can change a cell's division time, which in turn can change the population size. However, biochemical r…
Exactly Solvable Population Model with Square-Root Growth Noise and Cell-Size Regulation
Farshid Jafarpour
Stochastic exponential growth is nearly ubiquitous across cellular life, but how its microscopic noise structure shapes population growth remains poorly understood. Here, we introd…
Probing the Critical Point (CritPt) of AI Reasoning: a Frontier Physics Research Benchmark
Minhui Zhu, Minyang Tian, Xiaocheng Yang +61
While large language models (LLMs) with reasoning capabilities are progressing rapidly on high-school math competitions and coding, can they reason effectively through complex, ope…
Size-structured populations with growth fluctuations: Feynman--Kac formula and decoupling
Ethan Levien, Yaïr Hein, Farshid Jafarpour
We study a size-structured population model in which individual cells grow at a rate determined by a fluctuating internal variable (e.g., gene expression levels). Many previous mod…
Competition between transient oscillations and early stochasticity in exponentially growing populations
Yaïr Hein, Farshid Jafarpour
It has been recently shown that the exponential growth rate of a population of bacterial cells starting from a single cell shows transient oscillations due to early synchronized bu…
Asymptotic decoupling of population growth rate and cell size distribution
Yaïr Hein, Farshid Jafarpour
The rate at which individual bacterial cells grow depends on the concentrations of cellular components such as ribosomes and proteins. These concentrations continuously fluctuate o…
Cell size regulation induces sustained oscillations in the population growth rate
Farshid Jafarpour
We study the effect of correlations in generation times on the dynamics of population growth of microorganisms. We show that any non-zero correlation that is due to cell-size regul…
Biological timekeeping in the presence of stochasticity
Farshid Jafarpour, Michael Vennettilli, Srividya Iyer-Biswas
Causal ordering of key events in the cell cycle is essential for proper functioning of an organism. Yet, it remains a mystery how a specific temporal program of events is maintaine…
Phenomenology of stochastic exponential growth
Dan Pirjol, Farshid Jafarpour, Srividya Iyer-Biswas
Stochastic exponential growth is observed in a variety of contexts, including molecular autocatalysis, nuclear fission, population growth, inflation of the universe, viral social m…
Giant amplification of noise in fluctuation-induced pattern formation
Tommaso Biancalani, Farshid Jafarpour, Nigel Goldenfeld
The amplitude of fluctuation-induced patterns might be expected to be proportional to the strength of the driving noise, suggesting that such patterns would be difficult to observe…
A noise-induced mechanism for biological homochirality of early life self-replicators
Farshid Jafarpour, Tommaso Biancalani, Nigel Goldenfeld
The observed single-handedness of biological amino acids and sugars has long been attributed to autocatalysis. However, the stability of homochiral states in deterministic autocata…