activity
20172022
most citedEstimation of cell lineage trees by maximum-likelihood phylogenetics

13 citations · 23 across the 8 of their papers we have counts for

collaborators

8 papers

stat.ML20225 cited

Sequential algorithmic modification with test data reuse

Jean Feng, Gene Pennello, Nicholas Petrick +3

After initial release of a machine learning algorithm, the model can be fine-tuned by retraining on subsequently gathered data, adding newly discovered features, or more. Each modi…

stat.ML20211 cited

Bayesian logistic regression for online recalibration and revision of risk prediction models with performance guarantees

Jean Feng, Alexej Gossmann, Berkman Sahiner +1

After deploying a clinical prediction model, subsequently collected data can be used to fine-tune its predictions and adapt to temporal shifts. Because model updating carries risks…

stat.ML2020

Learning how to approve updates to machine learning algorithms in non-stationary settings

Jean Feng

Machine learning algorithms in healthcare have the potential to continually learn from real-world data generated during healthcare delivery and adapt to dataset shifts. As such, th…

stat.ML2020

Ensembled sparse-input hierarchical networks for high-dimensional datasets

Jean Feng, Noah Simon

Neural networks have seen limited use in prediction for high-dimensional data with small sample sizes, because they tend to overfit and require tuning many more hyperparameters tha…

stat.ML20193 cited

Approval policies for modifications to Machine Learning-Based Software as a Medical Device: A study of bio-creep

Jean Feng, Scott Emerson, Noah Simon

Successful deployment of machine learning algorithms in healthcare requires careful assessments of their performance and safety. To date, the FDA approves locked algorithms prior t…

q-bio.QM201913 cited

Estimation of cell lineage trees by maximum-likelihood phylogenetics

Jean Feng, William S DeWitt, Aaron McKenna +3

CRISPR technology has enabled large-scale cell lineage tracing for complex multicellular organisms by mutating synthetic genomic barcodes during organismal development. However, th…