4 papers
TriGlue: a Biology-Inspired Generative Model for Generating Molecular Glue-Induced Ternary Complex
Yuliang Yan, Shuo Yan, Haochun Tang +2
Molecular glue degraders have emerged as a promising strategy for targeted protein degradation by inducing ternary complex formation between an E3 ubiquitin ligase and a target pro…
Route to Rome Attack: Directing LLM Routers to Expensive Models via Adversarial Suffix Optimization
Haochun Tang, Yuliang Yan, Jiahua Lu +2
Cost-aware routing dynamically dispatches user queries to models of varying capability to balance performance and inference cost. However, the routing strategy introduces a new sec…
General Protein Pretraining or Domain-Specific Designs? Benchmarking Protein Modeling on Realistic Applications
Shuo Yan, Yuliang Yan, Bin Ma +6
Recently, extensive deep learning architectures and pretraining strategies have been explored to support downstream protein applications. Additionally, domain-specific models incor…
DuFFin: A Dual-Level Fingerprinting Framework for LLMs IP Protection
Yuliang Yan, Haochun Tang, Shuo Yan +1
Large language models (LLMs) are considered valuable Intellectual Properties (IP) for legitimate owners due to the enormous computational cost of training. It is crucial to protect…