2 papers
cs.LG2025
AReUReDi: Annealed Rectified Updates for Refining Discrete Flows with Multi-Objective Guidance
Tong Chen, Yinuo Zhang, Pranam Chatterjee
Designing sequences that satisfy multiple, often conflicting, objectives is a central challenge in therapeutic and biomolecular engineering. Existing generative frameworks largely…
cs.LG2025
Multi-Objective-Guided Discrete Flow Matching for Controllable Biological Sequence Design
Tong Chen, Yinuo Zhang, Sophia Tang +1
Designing biological sequences that satisfy multiple, often conflicting, functional and biophysical criteria remains a central challenge in biomolecule engineering. While discrete…