4 papers
Space-filling discrete helices
Jayanth R. Banavar, Achille Giacometti, Trinh X. Hoang +2
Proteins are linear chain molecules that play a central role in life and health. Protein native state folds are modular assemblies of space-filling building blocks of α-helices, \…
The protein escape process at the ribosomal exit tunnel has conserved mechanisms across the domains of life
Phuong Thuy Bui, Trinh Xuan Hoang
The ribosomal exit tunnel is the primary structure affecting the release of nascent proteins at the ribosome. The ribosomal exit tunnels from different species have elements of con…
Energetic preference and topological constraint effects on the formation of DNA twisted toroidal bundles
Nhung T. T. Nguyen, Anh T. Ngo, Trinh X. Hoang
DNA toroids are compact torus-shaped bundles formed by one or multiple DNA molecules being condensed from the solution due to various condensing agents. It has been shown that the…
Solvation enhances folding cooperativity and the topology dependence of folding rates in a lattice protein model
Nhung T. T. Nguyen, Pham Nam Phong, Duy Manh Le +2
The aqueous solvent profoundly influences protein folding, yet its effects are relatively poorly understood. In this study, we investigate the impact of solvation on the folding of…