3 papers
q-bio.CB2025
Robust assessment of asymmetric division in colon cancer cells
Domenico Caudo, Chiara Giannattasio, Simone Scalise +6
Asymmetric partition of fate determinants during cell division is a hallmark of cell differentiation. Recent work suggested that such a mechanism is hijacked by cancer cells to inc…
q-bio.CB2025
A mother-machine microfluidic device for non-adherent mammalian cells reveals the population growth strategies
Simone Scalise, Giovanna Peruzzi, Davide Caprini +3
We develop a mother machine-like microfluidic device specifically designed to track the proliferation of T-cells via live-cell microscopy. Although numerous microfluidic setups hav…
q-bio.CB2024
Probing leukemia cells behavior under starvation
Simone Scalise, Giorgio Gosti, Giancarlo Ruocco +2
The ability of a cancer cell population to achieve heterogeneity in their phenotype distributions offers advantages in tumor invasiveness and drug resistance. Studying the mechanis…