5 papers · 1 filter
Systems level circuit model of C. elegans undulatory locomotion: mathematical modeling and molecular genetics
Jan Karbowski, Gary Schindelman, Chris J. Cronin +2
To establish the relationship between locomotory behavior and dynamics of neural circuits in the nematode C. elegans we combined molecular and theoretical approaches. In particular…
Global and regional brain metabolic scaling and its functional consequences
Jan Karbowski
Background: Information processing in the brain requires large amounts of metabolic energy, the spatial distribution of which is highly heterogeneous reflecting complex activity pa…
Model of the early development of thalamo-cortical connections and area patterning via signaling molecules
Jan Karbowski, G. B. Ermentrout
The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by bot…
Towards comparative theoretical neuroanatomy of the cerebral cortex
Jan Karbowski
Despite differences in brain sizes and cognitive niches among mammals, their cerebral cortices posses many common features and regularities. These regularities have been a subject…
How does connectivity between cortical areas depend on brain size? Implications for efficient computation
Jan Karbowski
A formula for an average connectivity between cortical areas in mammals is derived. Based on comparative neuroanatomical data, it is found, surprisingly, that this connectivity is…