most citedGeneralized Haldane Equation and Fluctuation Theorem in the Steady State Cycle Kinetics of Single Enzymes

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cond-mat.stat-mech2005★ 59 cited

Generalized Haldane Equation and Fluctuation Theorem in the Steady State Cycle Kinetics of Single Enzymes

Hong Qian, X. Sunney Xie

Enyzme kinetics are cyclic. We study a Markov renewal process model of single-enzyme turnover in nonequilibrium steady-state (NESS) with sustained concentrations for substrates and…