6 papers
Breaking the Compression Ceiling: Data-Free Pipeline for Ultra-Efficient Delta Compression
Xiaohui Wang, Peng Ye, Chenyu Huang +5
With the rise of the fine-tuned-pretrained paradigm, storing numerous fine-tuned models for multi-tasking creates significant storage overhead. Delta compression alleviates this by…
Fitness aligned structural modeling enables scalable virtual screening with AuroBind
Zhongyue Zhang, Jiahua Rao, Jie Zhong +22
Most human proteins remain undrugged, over 96% of human proteins remain unexploited by approved therapeutics. While structure-based virtual screening promises to expand the druggab…
GUPNet++: Geometry Uncertainty Propagation Network for Monocular 3D Object Detection
Yan Lu, Xinzhu Ma, Lei Yang +6
Geometry plays a significant role in monocular 3D object detection. It can be used to estimate object depth by using the perspective projection between object's physical size and 2…
Model Decides How to Tokenize: Adaptive DNA Sequence Tokenization with MxDNA
Lifeng Qiao, Peng Ye, Yuchen Ren +5
Foundation models have made significant strides in understanding the genomic language of DNA sequences. However, previous models typically adopt the tokenization methods designed f…
COMET: Benchmark for Comprehensive Biological Multi-omics Evaluation Tasks and Language Models
Yuchen Ren, Wenwei Han, Qianyuan Zhang +13
As key elements within the central dogma, DNA, RNA, and proteins play crucial roles in maintaining life by guaranteeing accurate genetic expression and implementation. Although res…
BEACON: Benchmark for Comprehensive RNA Tasks and Language Models
Yuchen Ren, Zhiyuan Chen, Lifeng Qiao +10
RNA plays a pivotal role in translating genetic instructions into functional outcomes, underscoring its importance in biological processes and disease mechanisms. Despite the emerg…