2 papers
stat.ME2025
Bayesian adaptive randomization in the I-SPY2 sequential multiple assignment randomized trial
Peter Norwood, Christina Yau, Denise Wolf +4
The I-SPY2 phase 2 clinical trial is a long-running platform trial that evaluates neoadjuvant treatments for locally advanced breast cancer, assigning subjects to novel agents usin…
stat.ME2025
Independent increments and group sequential tests
Anastasios A. Tsiatis, Marie Davidian
Widely used methods and software for group sequential tests of a null hypothesis of no treatment difference that allow for early stopping of a clinical trial depend primarily on th…