2 papers
cs.LG2025
Multi-state Protein Design with DynamicMPNN
Alex Abrudan, Sebastian Pujalte Ojeda, Chaitanya K. Joshi +6
Structural biology has long been dominated by the one sequence, one structure, one function paradigm, yet many critical biological processes - from enzyme catalysis to membrane tra…
q-bio.BM2025
IgCraft: A versatile sequence generation framework for antibody discovery and engineering
Matthew Greenig, Haowen Zhao, Vladimir Radenkovic +2
Designing antibody sequences to better resemble those observed in natural human repertoires is a key challenge in biologics development. We introduce IgCraft: a multi-purpose model…