4 papers
RareLens: Towards End-to-End Rare Disease Care via Aligning Divergent Large Language Model Reasoning
Xi Chen, Hongru Zhou, Shiyu Feng +24
Rare diseases represent one of the most challenging settings for clinical decision-making, where heterogeneous presentations, sparse evidence and limited expertise create persisten…
RareAlert: Aligning heterogeneous large language model reasoning for early rare disease risk screening
Xi Chen, Hongru Zhou, Huahui Yi +10
Missed and delayed diagnosis remains a major challenge in rare disease care. At the initial clinical encounters, physicians assess rare disease risk using only limited information…
Evaluating the Diagnostic Classification Ability of Multimodal Large Language Models: Insights from the Osteoarthritis Initiative
Li Wang, Xi Chen, XiangWen Deng +4
Multimodal large language models (MLLMs) show promising performance on medical visual question answering (VQA) and report generation, but these generation and explanation abilities…
KOM: A Multi-Agent Artificial Intelligence System for Precision Management of Knee Osteoarthritis (KOA)
Weizhi Liu, Xi Chen, Zekun Jiang +11
Knee osteoarthritis (KOA) affects more than 600 million individuals globally and is associated with significant pain, functional impairment, and disability. While personalized mult…