2 papers
stat.AP2025
How can methods for classifying and clustering trajectories be used for prevention trials? An example in Alzheimer's disease area
Céline Bougel, Sébastien Déjean, Caroline Giulioli +3
Background: Clinical trials are designed to prove the efficacy of an intervention by means of model-based approaches involving parametric hypothesis testing. Issues arise when no e…
stat.ME2025
Medical Knowledge Integration into Reinforcement Learning Algorithms for Dynamic Treatment Regimes
Sophia Yazzourh, Nicolas Savy, Philippe Saint-Pierre +1
The goal of precision medicine is to provide individualized treatment at each stage of chronic diseases, a concept formalized by Dynamic Treatment Regimes (DTR). These regimes adap…